Télécharger le livre :  Voltage Gated Sodium Channels
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A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and...

Editeur : Springer
Parution : 2014-04-15
Collection : Handbook of Experimental Pharmacology
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346,80
Télécharger le livre :  Neurotrophic Factors
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This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome,...

Editeur : Springer
Parution : 2014-03-25
Collection : Handbook of Experimental Pharmacology
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346,80
Télécharger le livre :  Arrestins - Pharmacology and Therapeutic Potential
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This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The...

Editeur : Springer
Parution : 2013-11-29
Collection : Handbook of Experimental Pharmacology
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346,80
Télécharger le livre :  Pharmacotherapy of Pulmonary Hypertension
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This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification,...

Editeur : Springer
Parution : 2013-10-04
Collection : Handbook of Experimental Pharmacology
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406,80
Télécharger le livre :  Circadian Clocks
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This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.

Editeur : Springer
Parution : 2013-04-18
Collection : Handbook of Experimental Pharmacology
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466,80
Télécharger le livre :  Sphingolipids: Basic Science and Drug Development
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Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a...

Editeur : Springer
Parution : 2013-04-11
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Sphingolipids in Disease
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Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This  book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative...

Editeur : Springer
Parution : 2013-04-06
Collection : Handbook of Experimental Pharmacology
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250,80
Télécharger le livre :  Current Antipsychotics
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Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that...

Editeur : Springer
Parution : 2012-11-05
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Antibiotic Resistance
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This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are...

Editeur : Springer
Parution : 2012-10-22
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Sex and Gender Differences in Pharmacology
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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific...

Editeur : Springer
Parution : 2012-10-02
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Novel Antischizophrenia Treatments
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This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of...

Editeur : Springer
Parution : 2012-10-01
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Antiplatelet Agents
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Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet...

Editeur : Springer
Parution : 2012-08-23
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Heparin - A Century of Progress
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Heparins remain amongst the most commonly used drugs in clinical practice.  Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown...

Editeur : Springer
Parution : 2012-05-08
Collection : Handbook of Experimental Pharmacology
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346,80
Télécharger le livre :  Appetite Control
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The volume ‘Appetite Control’ provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism.  During the last decade, research in this area has produced a remarkable wealth of information and has...

Editeur : Springer
Parution : 2012-01-18
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Muscarinic Receptors
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Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and...

Editeur : Springer
Parution : 2012-01-06
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Pediatric Clinical Pharmacology
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The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of...

Editeur : Springer
Parution : 2011-09-01
Collection : Handbook of Experimental Pharmacology
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526,80
Télécharger le livre :  Histone Deacetylases: the Biology and Clinical Implication
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The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Editeur : Springer
Parution : 2011-08-31
Collection : Handbook of Experimental Pharmacology
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346,80
Télécharger le livre :  Phosphodiesterases as Drug Targets
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Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that...

Editeur : Springer
Parution : 2011-06-21
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Diabetes - Perspectives in Drug Therapy
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The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.

Editeur : Springer
Parution : 2011-04-11
Collection : Handbook of Experimental Pharmacology
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466,80
Télécharger le livre :  Urinary Tract
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The basic anatomy and physiology of the urinary tract, the validity of animal models and other methodological considerations as well as a range of potential therapeutic targets are comprehensively reviewed by leading international experts, making this a unique reference...

Editeur : Springer
Parution : 2011-02-04
Collection : Handbook of Experimental Pharmacology
ePub

346,80
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